Heterogeneous indications and the need for viability assessment: An international survey on the use of machine perfusion in liver transplantation.

ABSTRACT: Although machine perfusion (MP) is being increasingly adopted in liver transplantation, indications, timing, and modality are debated. To investigate current indications for MP a web-based Google Forms survey was launched in January 2021 and addressed to 127 experts in the field, identified among first and corresponding Authors of MP literature in the last 10 years. The survey presented 10 real-life cases of donor-recipient matching, asking whether the liver would be accepted (Q1), whether MP would be used in that particular setting (Q2) and, if so, by which MP modality (Q3) and at what timing during preservation (Q4). Respondents could also comment on each case. The agreement was evaluated using Krippendorff's alpha coefficient. Answers from 39 (30.1%) participants disclosed significant h

SUBMITTER: Patrono D 

PROVIDER: S-EPMC9291461 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature