Prenatal caffeine exposure: association with neurodevelopmental outcomes in 9- to 11-year-old children.

ABSTRACT:

Background

Despite the widespread use of caffeine including consumption during pregnancy, the effect of prenatal caffeine exposure on child brain development and behavior is unclear.

Methods

To address this, we used data from the Adolescent Brain and Cognitive Development Study (n = 11,875 children aged 9-11 years from 22 sites across the United States). We explored the associations between prenatal caffeine exposure and various developmental outcomes including birth outcomes, physical health, behavior problems, cognition, substance use and brain structure in children, and evaluated dose effects.

Results

Among 9,978 children (4,745 females) who had valid data for prenatal caffeine exposure and whose mothers did not use drugs of abuse after knowing of pregnancy, 4,170

SUBMITTER: Zhang R 

PROVIDER: S-EPMC9291501 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature