Thalamic Influence on Slow Wave Slope Renormalization During Sleep.

ABSTRACT:

Objective

Slow waves are thought to mediate an overall reduction in synaptic strength during sleep. The specific contribution of the thalamus to this so-called synaptic renormalization is unknown. Thalamic stroke is associated with daytime sleepiness, along with changes to sleep electroencephalography and cognition, making it a unique "experiment of nature" to assess the relationship between sleep rhythms, synaptic renormalization, and daytime functions.

Methods

Sleep was studied by polysomnography and high-density electroencephalography over 17 nights in patients with thalamic (n = 12) and 15 nights in patients with extrathalamic (n = 11) stroke. Sleep electroencephalographic overnight slow wave slope changes and their relationship with subjective daytime sleepiness, cognit

SUBMITTER: Jaramillo V 

PROVIDER: S-EPMC9291607 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature