Associations between psychosocial factors and circulating cytokines in breast cancer survivors.

ABSTRACT:

Objective

Research has established links between social isolation and heightened levels of proinflammatory cytokines (e.g., interleukin-6 [IL-6], tumour necrosis factor alpha [TNF-α]). Recent advances allow for the examination of cytokines that may also play a role in antiviral immunity (interferon-gamma [IFN-γ]). The present work explored how various features of social experience relate to circulating cytokines in breast cancer survivors, as inflammation has been tied to cancer recurrence and mortality.

Design

Female breast cancer survivors (N = 43) completed a blood draw to assess circulating levels of proinflammatory cytokines (IL-6, TNF-α) and levels of a cytokine that also relates to antiviral immunity (IFN-γ).

Main outcome measures

We examined association

SUBMITTER: Leschak CJ 

PROVIDER: S-EPMC9291725 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature