Cardiac output and peripheral vascular resistance during normotensive and hypertensive pregnancy - a systematic review and meta-analysis.

ABSTRACT:

Background

In-depth insight into haemodynamic changes during normotensive pregnancy may help identify women at risk for gestational hypertensive complications.

Objectives

To determine the magnitude of changes in cardiac output and its determinants stroke volume and heart rate, and total peripheral vascular resistance during singleton normotensive and hypertensive pregnancies.

Search strategy

PubMed (NCBI) and Embase (Ovid) databases were searched from their inception up to November 2019.

Selection criteria

Studies reporting original measurements of haemodynamic parameters during pregnancy together with a non-pregnant reference measurement. Studies including women using antihypertensive medication were excluded.

Data collection and analysis

Pooled mean di

SUBMITTER: Mulder EG 

PROVIDER: S-EPMC9291763 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature