Physical activity in asthma control and its immune modulatory effect in asthmatic preschoolers.

ABSTRACT:

Background

The impact of physical activity on immune response is a hot topic in exercise immunology, but studies involving asthmatic children are scarce. Our aims were to examine whether there were any differences in the level of physical activity and daily TV attendance, to assess its role on asthma control and immune responses to various immune stimulants.

Methods

Weekly physical activity and daily television attendance were obtained from questionnaires at inclusion of the PreDicta study. PBMC cultures were stimulated with phytohemagglutinin (PHA), R848, poly I:C, and zymosan. A panel of cytokines was measured and quantified in cell culture supernatants using luminometric multiplex immunofluorescence beads-based assay.

Results

Asthmatic preschoolers showed significa

SUBMITTER: Maurer DJ 

PROVIDER: S-EPMC9291774 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature