Time trends, geographic variation and risk factors for gastroschisis in Canada: A population-based cohort study 2006-2017.

ABSTRACT:

Background

Previous studies showed increases in rates of gastroschisis in Canada in the first decade of the 21st century.

Objective

We sought to examine the epidemiologic characteristics of gastroschisis in Canada in recent years.

Methods

We conducted a retrospective population-based cohort study of all livebirths and stillbirths delivered in Canada (excluding Quebec) from 2006 to 2017, with information obtained from the Canadian Institute for Health Information. Gastroschisis rates by maternal age, region of residence, and maternal and infant characteristics were quantified using prevalence rate ratios (RR) and 95% confidence intervals (CI). Log-binomial regression was used to quantify the associations between risk factors and gastroschisis.

Results

There were

SUBMITTER: Liu S 

PROVIDER: S-EPMC9291817 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature