Clinical safety and efficacy of bispecific antibody in the treatment of solid tumors: A protocol for a systematic review.

ABSTRACT:

Background

Cancers are among the most common causes of mortality and morbidity. Recently, bispecific antibodies (BsAbs) have been used for cancer treatment. The aim of this systematic review and meta-analysis will be to determine the safety and efficacy of BsAbs in the treatment of solid tumors.

Methods

We will search five electronic databases, PubMed, EMBASE, Scopus, Web of Science, and CENTRAL, in addition to Clinical-Trials.gov and metaRegister of controlled trials and backward and forward citation searching of included studies. Eligible studies will be controlled clinical trials evaluating safety and/or efficacy of BsAbs in adult patients with solid tumors. The primary outcomes will be the incidence of safety and efficacy measures. Title and/or abstract screening, full t

SUBMITTER: Nejadghaderi SA 

PROVIDER: S-EPMC9292075 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature