Causal factors affecting gross motor function in children diagnosed with cerebral palsy.

ABSTRACT:

Background

Cerebral palsy (CP) is a complex neuromuscular condition that may negatively influence gross motor function. Children diagnosed with CP often exhibit spasticity, weakness, reduced motor control, contracture, and bony malalignment. Despite many previous association studies, the causal impact of these impairments on motor function is unknown.

Aim

In this study, we proposed a causal model which estimated the effects of common impairments on motor function in children with spastic CP as measured by the 66-item Gross Motor Function Measure (GMFM-66). We estimated both direct and total effect sizes of all included variables using linear regression based on covariate adjustment sets implied by the minimally sufficient adjustment sets. In addition, we estimated bivariate

SUBMITTER: MacWilliams BA 

PROVIDER: S-EPMC9292109 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature