Comparison of 6-month vascular healing response after bioresorbable polymer versus durable polymer drug-eluting stent implantation in patients with acute coronary syndromes: A randomized serial optical coherence tomography study.

ABSTRACT:

Objectives

This study was conducted to use optical coherence tomography (OCT) to compare vascular healing between bioresorbable polymer (BP) and durable polymer (DP) everolimus-eluting stents (EES) in patients with acute coronary syndromes (ACS).

Background

Whether BP-EES induce better vascular healing compared to contemporary DP-EES remains controversial, especially for ACS.

Methods

In this prospective, randomized, non-inferiority trial, we used OCT to compare 6-month vascular healing in patients with ACS randomized to BP versus DP-EES: percent strut coverage (primary endpoint, non-inferiority margin of 2.0%) and neointimal thickness and percent neointimal hyperplasia (NIH) volume. As an exploratory analysis, morphological factors related to the endpoints and the eff

SUBMITTER: Noguchi M 

PROVIDER: S-EPMC9292175 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature