Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.

ABSTRACT: Magnesium status and vitamin B6 intake have been linked to mental health and/or quality of life (QoL). In an 8-week Phase IV randomised controlled study in individuals with low magnesemia and severe/extremely severe stress but who were otherwise healthy, greater stress reduction was achieved with magnesium combined with vitamin B6 than with magnesium alone. We present a previously unreported secondary analysis of the effect of magnesium, with and without vitamin B6, on depression, anxiety, and QoL. Adults with Depression Anxiety Stress Scales (DASS-42) stress subscale score >18 were randomised 1:1 to magnesium + vitamin B6 combination (Magne B6^® ; daily dose 300 and 30 mg, respectively) or magnesium alone (Magnespasmyl^® ; daily dose 300 mg). Outcomes included changes

SUBMITTER: Noah L 

PROVIDER: S-EPMC9292249 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature