The bidirectional longitudinal association between depressive symptoms and HbA_1c : A systematic review and meta-analysis.

ABSTRACT:

Aim

To investigate whether there is a bidirectional longitudinal association of depression with HbA_1c .

Methods

We conducted a systematic literature search in PubMed, PsycINFO, CINAHL and EMBASE for observational, longitudinal studies published from January 2000 to September 2020, assessing the association between depression and HbA_1c in adults. We assessed study quality with the Newcastle-Ottawa-Scale. Pooled effect estimates were reported as partial correlation coefficients (r_p ) or odds ratios (OR).

Results

We retrieved 1642 studies; 26 studies were included in the systematic review and eleven in the meta-analysis. Most studies (16/26) focused on type 2 diabetes. Study quality was rated as good (n = 19), fair (n = 2) and poor (n = 5

SUBMITTER: Beran M 

PROVIDER: S-EPMC9292323 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature