Delete and survive: strategies of programmed genetic material elimination in eukaryotes.

ABSTRACT: Genome stability is a crucial feature of eukaryotic organisms because its alteration drastically affects the normal development and survival of cells and the organism as a whole. Nevertheless, some organisms can selectively eliminate part of their genomes from certain cell types during specific stages of ontogenesis. This review aims to describe the phenomenon of programmed DNA elimination, which includes chromatin diminution (together with programmed genome rearrangement or DNA rearrangements), B and sex chromosome elimination, paternal genome elimination, parasitically induced genome elimination, and genome elimination in animal and plant hybrids. During programmed DNA elimination, individual chromosomal fragments, whole chromosomes, and even entire parental genomes can be selectively re

SUBMITTER: Dedukh D 

PROVIDER: S-EPMC9292451 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature