The maternal diet index in pregnancy is associated with offspring allergic diseases: the Healthy Start study.

ABSTRACT:

Background

A systematic review showed limited associations between pregnancy diet and offspring allergy. We developed a maternal diet index during pregnancy that was associated with offspring allergy outcomes.

Methods

Data came from Healthy Start, a Colorado pre-birth cohort of mother/offspring dyads. Food propensity questionnaires were completed during pregnancy. Offspring allergic rhinitis, atopic dermatitis, asthma, wheeze, and food allergy diagnosis up to age four were verified from electronic medical records. Data were randomized into test and replication sets. The index included the weighted combination of variables that best predicted a combined outcome of any allergy in the test set. Index utility was verified in the replication set. Separate adjusted and unadjusted

SUBMITTER: Venter C 

PROVIDER: S-EPMC9292464 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature