Evaluating the longitudinal effect of colorectal surgery on health-related quality of life in patients with colorectal cancer.

ABSTRACT:

Background and objectives

Surgery for colorectal cancer (CRC) negatively affects health-related quality of life (HRQoL). Addressing shortcomings in literature, the purpose of this study was to evaluate the impact of surgery for CRC on the course of HRQoL from baseline up to 2 years after diagnosis.

Methods

In this prospective, population-based study patients with newly diagnosed CRC were included between 2016 and 2019. HRQoL was assessed by the EORTC QLQ-C30 questionnaire over time both between and within subgroups of patients that underwent right-sided colonic, left-sided colonic, and rectal resection using linear mixed model analyses.

Results

The study included 415 patients of whom 148 patients underwent right-sided colonic (36%), 147 left-sided colonic (35%), and 1

SUBMITTER: Reudink M 

PROVIDER: S-EPMC9292688 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature