Relation of Pre-Stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes.

ABSTRACT:

Objective

We investigated (1) the associations of pre-stroke aspirin use with thrombus burden, infarct volume, hemorrhagic transformation, early neurological deterioration (END), and functional outcome, and (2) whether stroke subtypes modify these associations in first-ever ischemic stroke.

Methods

This multicenter magnetic resonance imaging (MRI)-based study included 5,700 consecutive patients with acute first-ever ischemic stroke, who did not undergo intravenous thrombolysis or endovascular thrombectomy, from May 2011 through February 2014. Propensity score-based augmented inverse probability weighting was performed to estimate adjusted effects of pre-stroke aspirin use.

Results

The mean age was 67 years (41% women), and 15.9% (n = 907) were taking aspirin before st

SUBMITTER: Ryu WS 

PROVIDER: S-EPMC9292882 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature