Impact of a mid-urethral synthetic mesh sling on long-term risk of systemic conditions in women with stress urinary incontinence: a national cohort study.

ABSTRACT:

Objective

To compare the incidence of systemic conditions between women who had surgical treatment for stress incontinence with mesh and without mesh.

Design

National cohort study.

Setting

English National Health Service.

Population

Women with no previous record of systemic disease who had first-time urinary incontinence surgery between 1 January 2006 and 31 December 2013, followed up to the earliest of 10 years or 31 March 2019.

Methods

Competing-risks regression was used to estimate hazard ratios (HR), adjusted for patient characteristics, with HR > 1 indicating increased incidence following mesh surgery.

Main outcome measures

First postoperative admission with a record of autoimmune disease, fibromyalgia or myalgic encephalomyelitis up to 10 ye

SUBMITTER: Muller P 

PROVIDER: S-EPMC9292923 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature