Effectiveness of Prophylactic Preoperative Antibiotics in Mandible Fracture Repair: A National Database Study.

ABSTRACT:

Objective

This is the first database study to assess the effectiveness of prophylactic preoperative antibiotics (PPAs) in mandible fracture repair.

Study design

Retrospective cohort.

Setting

Database study using US inpatient and outpatient insurance claims submitted from July 2006 to March 2015.

Methods

The IBM MarketScan Commercial Database was queried for adults aged 18 to 64 years who had undergone first-time mandible fracture repair according to Current Procedural Terminology codes for open and closed repair. Primary outcomes included surgical revision, local infection, and osteomyelitis. Rates were compared between cohorts based on whether or not patients had filled antibiotic prescriptions during the preoperative period alone. The effects of drug a

SUBMITTER: Wick EH 

PROVIDER: S-EPMC9293062 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature