Clinical and immunological evaluation of cat-allergic asthmatics living with or without a cat.

ABSTRACT:

Background

Characterising the clinical and immunological impact of daily cat exposure in cat-allergic subjects with asthma who live with cats (WC) and those who do not (WoC) may provide understanding of the drivers of the allergic response.

Methods

Clinical and immunological characteristics (skin prick test, spirometry, symptom assessments, immunological markers) were compared between asthmatic subjects WC (n = 10) and WoC (n = 9).

Results

WC subjects had greater use of long-acting beta agonists (p < .05) and high-potency corticosteroids. No differences were observed in lung function, nasal and ocular symptoms, or asthma control between the groups. Cat dander- and Fel d 1-specific IgG₄ concentrations were higher in WC than WoC subjects (both p < .05). Total

SUBMITTER: Wambre ER 

PROVIDER: S-EPMC9293312 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature