The effect of prenatal lithium exposure on the neuropsychological development of the child.

ABSTRACT:

Objectives

Lithium is an effective treatment for bipolar disorder, also during pregnancy to prevent the recurrence of episodes in the perinatal period. Little is known about the neuropsychological development of lithium-exposed offspring. The current study was designed to investigate neuropsychological functioning in lithium-exposed children with the aim to provide further knowledge on the long-term effects of lithium use during pregnancy.

Methods

Participants were offspring of women with a diagnosis of bipolar spectrum disorder, aged 6-14 years. In total, 99 children participated in the study, 56 were exposed to lithium in utero and 43 were not exposed to lithium. Neuropsychological tests were administered, including the Snijders-Oomen Nonverbal Intelligence Test and the NE

SUBMITTER: Poels EMP 

PROVIDER: S-EPMC9293321 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature