Development and validation of the dialysis dementia risk score: A retrospective, population-based, nested case-control study.

ABSTRACT:

Background

Dementia is prevalent and underdiagnosed in the dialysis population. We aimed to develop and validate a simple dialysis dementia scoring system to facilitate identification of individuals who are at high risk for dementia.

Methods

We applied a retrospective, nested case-control study design using a national dialysis cohort derived from the National Health Insurance Research Database in Taiwan. Patients aged between 40 and 80 years were included and 2940 patients with incident dementia were matched to 29,248 non-dementia controls. All subjects were randomly divided into the derivation and validation sets with a ratio of 4:1. Conditional logistic regression models were used to identify factors contributing to the risk score. The cutoff value of the risk score was de

SUBMITTER: Ling TC 

PROVIDER: S-EPMC9293339 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature