Intraoperative hypotension and delirium among older adults undergoing transcatheter aortic valve replacement.

ABSTRACT:

Background

Postoperative delirium (POD) is a frequently observed complication after transcatheter aortic valve replacement (TAVR). The effects of intraoperative hypotension (IOH) on POD occurrence are currently unclear.

Methods

A retrospective observational cohort study of patients who underwent TAVR was conducted. We predefined IOH as area under the threshold (AUT) of five mean arterial blood pressures (MBP), varying from <100 to <60 mmHg. The AUT consisted of the combination of duration and depth under the MBP thresholds, expressed in mmHg*min. All MBP AUTs were computed based on the complete procedure, independent of procedural phase or duration.

Results

This cohort included 675 patients who underwent TAVR under general anesthesia (n = 128, 19%) or procedural sedat

SUBMITTER: Wesselink EM 

PROVIDER: S-EPMC9293424 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature