Heart failure with preserved ejection fraction after left-sided valve surgery: prevalent and relevant.

ABSTRACT:

Aims

To investigate the epidemiological and prognostic relationship between heart failure with preserved ejection fraction (HFpEF) and left-sided valve surgery using all-cause mortality as a primary endpoint.

Methods and results

We studied a total of 973 patients, of whom 673 had undergone left-sided valve surgery (time from surgery to enrolment 50 ± 30 months after valve surgery) and 300 patients with HFpEF without prior surgery served as control group. Among patients after surgery, 67.4% fulfilled all criteria of HFpEF according to current guideline recommendations, 20.6% had no heart failure (HF), and 12.0% had HF with mid-range or reduced ejection fraction (HFmrEF/HFrEF). During 83 ± 39 months of follow-up, a total of 335 (34.4%) patients died. Compared to surgical patie

SUBMITTER: Kammerlander AA 

PROVIDER: S-EPMC9293454 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature