Mechanical versus bioprosthetic valves in chronic dialysis: a systematic review and meta-analysis.

ABSTRACT:

Background

Many patients with end-stage kidney disease (ESKD) have valvular heart disease requiring surgery. The optimal prosthetic valve is not established in this population. We performed a systematic review and meta-analysis to assess outcomes of patients with dialysis-dependent ESKD who received mechanical or bioprosthetic valves.

Methods

We searched Cochrane Central, Medline and Embase from inception to January 2020. We performed screening, full-text assessment, risk of bias and data collection, independently and in duplicate. Data were pooled using a random-effects model.

Results

We identified 28 observational studies (n = 9857 patients, including 6680 with mechanical valves and 3717 with bioprosthetic valves) with a median follow-up of 3.45 years. Twenty

SUBMITTER: Kim KS 

PROVIDER: S-EPMC9293484 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature