Study of Correlation between Intestinal Microbiota and Traditional Chinese Medicine Syndrome of Patients with Colon Cancer.

ABSTRACT:

Objective

This research aims to study the material basis of the formation and specific bacteria of traditional Chinese medicine (TCM) syndrome from the characteristics of the intestinal microbiota of patients with colon cancer (CC) before and after the operation.

Methods

A cross-sectional study was conducted on 84 patients with CC and 24 healthy controls. A total of 168 and 24 stool samples were collected from CC patients before and after the operation and healthy controls. DNA was extracted from 192 stool samples and then amplified using PCR. The V3-V4 high variable areas were analyzed by 16s rDNA sequencing.

Results

The community diversity, in descending order, was the healthy control group and postoperative and preoperative groups of CC patients. The abundance of b

SUBMITTER: Tuo LY 

PROVIDER: S-EPMC9293549 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature