Radiotherapy for glioblastoma patients with poor performance status.

ABSTRACT:

Purpose

There is limited information on treatment recommendations for glioblastoma patients with poor performance status. Here, we aim to evaluate the association of radiotherapy on survival in glioblastoma patients presenting with poor postoperative performance status in first-line setting.

Methods

We retrospectively analyzed data of 93 glioblastoma patients presenting with poor postoperative performance status (ECOG 2-4) at the University Hospital Zurich, Switzerland, in the years 2005-2019. A total of 43 patients received radiotherapy with or without systemic therapy in the first-line setting, whereas 50 patients received no additive local or systemic treatment after initial biopsy or resection. Overall survival was calculated from primary diagnosis and from the end of ra

SUBMITTER: Schroder C 

PROVIDER: S-EPMC9293860 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature