Preparation and Biocompatibility Study of Contrast-Enhanced Hernia Mesh Material.

ABSTRACT:

Background

Meshes play a crucial role in hernia repair. However, the displacement of mesh inevitably leads to various associated complications. This process is difficult to be traced by conventional imaging means. The purpose of this study is to create a contrast-enhanced material with high-density property that can be detected by computed tomography (CT).

Methods

The contrast-enhanced monofilament was manufactured from barium sulfate nanoparticles and medical polypropylene (PP/Ba). To characterize the composite, stress tensile tests and scanning electron microscopy (SEM) was performed. Toxicity and biocompatibility of PP/Ba materials was verified by in vitro cellular assays. Meanwhile, the inflammatory response was tested by protein adsorption assay. In addition, an animal

SUBMITTER: Ding X 

PROVIDER: S-EPMC9294108 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature