Isolation of Haematococcus lacustris as source of novel anti-multi-antibiotic resistant microbes agents; fractionation and identification of bioactive compounds.

ABSTRACT: In this work, freshwater microalga, Haematococcus lacustris was isolated from the River Nile, identified and deposited in genebank under name of H. lacustris isolate REH10 with accession number OK336515. N-hexane extract was produced high inhibition effects against multi-antibiotic resistant pathogens. The n-Hexane extract was fractionated and 2 fractions (F3 & F4) exhibited high antibacterial activity (15 - 20 mm) compared with other fractions. Thus, they sub-fractionated and 2 sub-fractions produced from the F3 had high inhibition activity against all tested pathogens (18-20 mm). To identify the main compounds responsible for inhibition growth of multi-drug resistance bacteria, GC-MS chromatogram analyses was applied on the F3 and its sub-fractions 2 and 3. Five compounds d

SUBMITTER: Darwesh OM 

PROVIDER: S-EPMC9294494 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature