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The Antibacterial, Antitumor Activities, and Bioactive Constituents' Identification of Alectra sessiliflora Bacterial Endophytes.


ABSTRACT: Due to increased antimicrobial resistance against current drugs, new alternatives are sought. Endophytic bacteria associated with medicinal plants are recognized as valuable sources of novel secondary metabolites possessing antimicrobial, antitumor, insecticidal, and antiviral activities. In this study, five bacterial endophytes were isolated and identified from the medicinal plant, Alectra sessiliflora, and their antibacterial and antitumor activities were investigated. In addition, the crude extracts of the endophytes were analyzed using gas chromatography (GC) coupled with time-of-flight mass spectrometry (TOF-MS). The identified bacterial endophytes belong to three genera viz Lysinibacillus, Peribacillus, and Bacillus, with the latter as the dominant genus with thr

SUBMITTER: Maela MP 

PROVIDER: S-EPMC9294510 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature