Cost-effectiveness analysis of colorectal cancer screening in Shanghai, China: A modelling study.

ABSTRACT:

Background

The current community-based colorectal cancer (CRC) screening program in Shanghai, launched in 2013, invited individuals aged 50-74 years to triennial screening with a qualitative faecal immunochemical test (FIT) and questionnaire-based risk assessment (RA). We aimed to evaluate the effectiveness and cost-effectiveness of the existing Shanghai screening program and compare it to using a validated two-sample quantitative FIT.

Methods

We simulated four strategies (no screening, Shanghai FIT, Shanghai FIT + RA and validated FIT) for the Shanghai screening program and evaluated CRC incidence, CRC mortality, the number of life years gained (LYG), the number of FITs, and colonoscopies required for each. An incremental cost-effectiveness analysis was performed to assess

SUBMITTER: Wang J 

PROVIDER: S-EPMC9294625 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature