Tidal volume challenge to predict preload responsiveness in patients with acute respiratory distress syndrome under prone position.

ABSTRACT:

Background

Prone position is frequently used in patients with acute respiratory distress syndrome (ARDS), especially during the Coronavirus disease 2019 pandemic. Our study investigated the ability of pulse pressure variation (PPV) and its changes during a tidal volume challenge (TVC) to assess preload responsiveness in ARDS patients under prone position.

Methods

This was a prospective study conducted in a 25-bed intensive care unit at a university hospital. We included patients with ARDS under prone position, ventilated with 6 mL/kg tidal volume and monitored by a transpulmonary thermodilution device. We measured PPV and its changes during a TVC (ΔPPV TVC_6-8) after increasing the tidal volume from 6 to 8 mL/kg for one minute. Changes in cardiac index (CI) during

SUBMITTER: Shi R 

PROVIDER: S-EPMC9294836 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature