Antenatal Magnesium Sulfate for Preterm Neuroprotection: A Single-Center Experience from Kuwait Tertiary NICU.

ABSTRACT:

Objectives

The study aimed to evaluate the impact of antenatal exposure of magnesium sulfate (MgSO₄) on short- and long-term outcomes in preterm neonates born less than 32 weeks gestation.

Methods

Single-center retrospective cohort study of 229 neonates born between 24 and 32 weeks gestation was conducted from January 2018 through December 2018 in a level III neonatal care unit in Kuwait. Antenatal MgSO₄ exposure was collected from the medical records, and the indication was for neuroprotection effect. Brain MRI was done on 212 neonates (median gestational age 36 weeks), and brain injury was assessed using the Miller's score. Neurodevelopmental outcome was assessed by Bayley-III scales of infant development at 36 months corrected age (N = 146). T

SUBMITTER: Ayed M 

PROVIDER: S-EPMC9294943 | biostudies-literature | 2022 May-Aug

REPOSITORIES: biostudies-literature