Cytokine Expression in Staphylococcal and Streptococcal Endophthalmitis.

ABSTRACT:

Background

Endophthalmitis is an infection of ocular tissues, often with devastating outcomes for vision. Immunomodulation is an emerging avenue for therapeutic intervention in endophthalmitis, with the expression of cytokines central to potential mechanisms. This literature review with a systematic approach characterizes the cytokine expression in both animal and human staphylococcal and streptococcal endophthalmitis.

Method and results

Four online databases were searched for studies profiling cytokine levels in animal models or human populations with staphylococcal and/or streptococcal endophthalmitis. Of the 1,060 articles identified, 14 studies were included in this review comprising eight animal models and six human populations. Mouse, rat, and rabbit models of Staph

SUBMITTER: Soon MY 

PROVIDER: S-EPMC9294960 | biostudies-literature | 2022 May-Aug

REPOSITORIES: biostudies-literature