COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant women.

ABSTRACT:

Background

Although emerging data during the SARS-CoV-2 pandemic have demonstrated robust messenger RNA vaccine-induced immunogenicity across populations, including pregnant and lactating individuals, the rapid waning of vaccine-induced immunity and the emergence of variants of concern motivated the use of messenger RNA vaccine booster doses. Whether all populations, including pregnant and lactating individuals, will mount a comparable response to a booster dose is not known.

Objective

This study aimed to profile the humoral immune response to a COVID-19 messenger RNA booster dose in a cohort of pregnant, lactating, and nonpregnant age-matched women.

Study design

This study characterized the antibody response against ancestral Spike and Omicron in a cohort of 31 pregn

SUBMITTER: Atyeo C 

PROVIDER: S-EPMC9295313 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature