Combining L-Arginine with vitamin C improves long-COVID symptoms: The LINCOLN Survey.

ABSTRACT:

Introduction

Recent evidence suggests that oxidative stress and endothelial dysfunction play critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a supplementation combining L-Arginine (to improve endothelial function) and Vitamin C (to reduce oxidation) could have favorable effects on Long-COVID symptoms.

Methods

We designed a survey (LINCOLN: L-Arginine and Vitamin C improves Long-COVID), assessing several symptoms that have been associated with Long-COVID to be administered nationwide to COVID-19 survivors; the survey also included effort perception, measured using the Borg scale. Patients receiving the survey were divided in two groups, with a 2:1 ratio: the first group included patients that received L-Arginine + Vitamin C, whereas the

SUBMITTER: Izzo R 

PROVIDER: S-EPMC9295384 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature