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Characterization of Extended-Spectrum β-Lactamase-Producing Shigella sonnei in Spain: Expanding the Geographic Distribution of Sequence Type 152/CTX-M-27 Clone.


ABSTRACT: We describe the first occurrence in Spain of community cases of CTX-M-27-producing Shigella sonnei sequence type 152 (ST152), resistant to quinolones and azithromycin. The cases included adult males and also one pediatric case. The isolates were clustered together with an Australian isolate and differed from other outbreak-causing strains in England by more than 50 alleles. They carried the blaCTX-M-27 gene on an 83-Kb F2:A-:B- plasmid, similar to that found in a British isolate.

SUBMITTER: Lopez-Cerero L 

PROVIDER: S-EPMC9295536 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Characterization of Extended-Spectrum β-Lactamase-Producing Shigella sonnei in Spain: Expanding the Geographic Distribution of Sequence Type 152/CTX-M-27 Clone.

López-Cerero Lorena L   Stolz Emilio E   Pulido Marina R MR   Pascual Alvaro A  

Antimicrobial agents and chemotherapy 20220628 7


We describe the first occurrence in Spain of community cases of CTX-M-27-producing Shigella sonnei sequence type 152 (ST152), resistant to quinolones and azithromycin. The cases included adult males and also one pediatric case. The isolates were clustered together with an Australian isolate and differed from other outbreak-causing strains in England by more than 50 alleles. They carried the <i>bla</i><sub>CTX-M-27</sub> gene on an 83-Kb F2:A-:B- plasmid, similar to that found in a British isolat  ...[more]

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