Smoking and smoking cessation in disadvantaged women: assessing genetic contributions.

ABSTRACT: Abundant evidence from family, adoption and twin studies points to large genetic contributions to individual differences in vulnerability to develop dependence on one or more addictive substances, including tobacco. Twin data suggests that much of this genetic vulnerability is shared by individuals who are dependent on a variety of addictive substances. Interestingly, some twin data also supports substantial differences in the apparent heritability of nicotine dependence in women as environmental conditions become more permissive for their smoking. In addition, twin studies also support the idea that ability to quit smoking displays substantial heritability, and that this heritable influence overlaps partially with genetic influences on nicotine dependence. Candidate gene molecular genetic

SUBMITTER: Uhl GR 

PROVIDER: S-EPMC9295906 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature