Availability of vitamin B₁₂ and its lower ligand intermediate α-ribazole impact prokaryotic and protist communities in oceanic systems.

ABSTRACT: Genome analyses predict that the cofactor cobalamin (vitamin B₁₂, called B₁₂ herein) is produced by only one-third of all prokaryotes but almost all encode at least one B₁₂-dependent enzyme, in most cases methionine synthase. This implies that the majority of prokaryotes relies on exogenous B₁₂ supply and interacts with producers. B₁₂ consists of a corrin ring centred around a cobalt ion and the lower ligand 5'6-dimethylbenzimidazole (DMB). It has never been tested whether availability of this pivotal cofactor, DMB or its intermediate α-ribazole affect growth and composition of prokaryotic microbial communities. Here we show that in the subtropical, equatorial and polar frontal Pacific Ocean supply of B₁₂ and α-ribazole enha

SUBMITTER: Wienhausen G 

PROVIDER: S-EPMC9296465 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature