Structural features of subchondral bone cysts and adjacent tissues in hip osteoarthritis.

ABSTRACT:

Objective

Focal lesions within the subchondral bone, termed subchondral bone cysts (SBCs), are clinically accepted radiographic markers of advanced osteoarthritis (OA), but their etiology in the hip is not well understood.

Design

This study used micro-computed tomography (μCT), and histological and immunocytological analysis to examine the prevalence, size, location, and morphological and cellular features of SBCs found within 34 femoral heads (14 male, 20 female; age range = 43-80 years) obtained from total hip arthroplasty procedures.

Results

SBCs were common-present in 91% of the femoral heads examined-and frequently commuted with the surface of the femoral head, but otherwise showed no preferred anatomical location. Few associations were found between SBC features

SUBMITTER: Nakasone A 

PROVIDER: S-EPMC9296569 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature