Outcomes Analyses of Pediatric Acute Liver Failure Subjects Listed for Liver Transplantation.

ABSTRACT:

Background

We characterized recent outcomes in US pediatric acute liver failure (PALF) subjects listed for liver transplantation (LT) using the Scientific Registry of Transplant Recipients (SRTR) database.

Methods

Pediatric subjects listed for LT from 2002 to 2015 were assigned to the "PALF" group based on status 1/1A listing, INR >2, no hepatic artery thrombosis, and no primary graft nonfunction (N = 397). Subjects were assigned to the "non-PALF" group if listed with any status other than 1/1A (N = 4509).

Results

The PALF group had more infants <3 months of age and males at listing for LT compared to the non-PALF group. Two-thirds of PALF subjects had an indeterminate etiology. LT waitlist survival was significantly worse in the PALF group compared to the non-PALF gr

SUBMITTER: Kulkarni SS 

PROVIDER: S-EPMC9296584 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature