Effectiveness of automated alerting system compared to usual care for the management of sepsis.

ABSTRACT: There is a large body of evidence showing that delayed initiation of sepsis bundle is associated with adverse clinical outcomes in patients with sepsis. However, it is controversial whether electronic automated alerts can help improve clinical outcomes of sepsis. Electronic databases are searched from inception to December 2021 for comparative effectiveness studies comparing automated alerts versus usual care for the management of sepsis. A total of 36 studies are eligible for analysis, including 6 randomized controlled trials and 30 non-randomized studies. There is significant heterogeneity in these studies concerning the study setting, design, and alerting methods. The Bayesian meta-analysis by using pooled effects of non-randomized studies as priors shows a beneficial effect of the aler

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC9296632 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature