Association of Body Mass Index with Survival in Asian Patients with Colorectal Cancer.

ABSTRACT:

Purpose

The clinical significance of body mass index (BMI) on long-term outcomes has not been extensively investigated in Asian patients with colorectal cancer (CRC). This study aims to describe the association between BMI and survival, plus providing BMI cut-off value for predicting prognosis in CRC patients.

Materials and methods

A total of 1,182 patients who had undergone surgery for stage I-III CRC from June 2004 to February 2014 were included. BMI was categorized into four groups based on the recommendation for Asian ethnicity. The optimal BMI cut-off value was determined to maximize overall survival (OS) difference.

Results

In multivariable analysis, underweight BMI was significantly associated with poor OS (hazard ratio [HR], 2.38; 95% confidence interval [CI],

SUBMITTER: Lee S 

PROVIDER: S-EPMC9296949 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature