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The first years of liver transplantation: experiences at a single center.


ABSTRACT:

Background

The aim of this study was to analyze the first stages of progress in liver transplantation (LT) at a single center in Vietnam.

Methods

This study analyzed data from patients and donors who participated in the LT program between August 2018 and December 2021 at University Medical Center, Ho Chi Minh City. Study measures included any difficulties encountered, as well as the post-LT outcomes for living donor LT (LDLT) and deceased donor LT (DDLT). The chi-square test and Kaplan Meier survival analysis were used to test the factors that influenced the outcomes.

Results

A total of 18 adult recipients with LT (LDLT, n=16; DDLT, n=2) were included (mean age, 55.2±2.6 years; male, 88.9%). The most common post-LT complications were middle hepatic venous stenosis (20%) and graft rejection (22.2%). These complications were observed in LDLT patients. For DDLT, graft rejection (50%) was the only complication recorded. The survival rates for recipients at 3 months, 6 months, and 1 year were 100%, 88.9%, and 88.9%, respectively. The LDs had their right livers without the middle hepatic veins harvested, and biliary leakage (6.25%) was the only complication observed. There were no deaths among recipients or LDs during the operations or hospital stays.

Conclusions

This study provides key details about the process of LT, and these positive outcomes support LT as an important therapy for end-stage liver disease and early hepatocellular carcinomas.

SUBMITTER: Pham PH 

PROVIDER: S-EPMC9297033 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

The first years of liver transplantation: experiences at a single center.

Pham Phu Hong PH   Phan Nghia Phuoc NP   Tran Viet Doan Khac VDK   Dang Viet Quoc VQ   Le Dat Tien DT   Nguyen Thuan Duc TD   Tran Long Cong Duy LCD   Nguyen Bac Hoang BH  

Korean journal of transplantation 20220601 2


<h4>Background</h4>The aim of this study was to analyze the first stages of progress in liver transplantation (LT) at a single center in Vietnam.<h4>Methods</h4>This study analyzed data from patients and donors who participated in the LT program between August 2018 and December 2021 at University Medical Center, Ho Chi Minh City. Study measures included any difficulties encountered, as well as the post-LT outcomes for living donor LT (LDLT) and deceased donor LT (DDLT). The chi-square test and K  ...[more]

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