Examination of Common Coronavirus Antibodies in SARS-CoV-2-Infected and Uninfected Participants in a Household Transmission Investigation.
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ABSTRACT:
SUBMITTER: Stumpf MM
PROVIDER: S-EPMC9297157 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
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Examination of Common Coronavirus Antibodies in SARS-CoV-2-Infected and Uninfected Participants in a Household Transmission Investigation.
Stumpf Megan M MM Freeman Brandi B Mills Lisa L Lester Sandra S Chu Victoria T VT Kirking Hannah L HL Thornburg Natalie J NJ Killerby Marie E ME
Open forum infectious diseases 20220720 7
We compared paired serum specimens from household contacts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases with detectable SARS-CoV-2 seroconversion with contacts who remained seronegative. No protection from SARS-CoV-2 infection was associated with human coronavirus antibodies; however, an increase in common betacoronavirus antibodies was associated with seroconversion to SARS-CoV-2 in mild to moderately ill cases. ...[more]
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