Postoperative Adjuvant Chemoradiotherapy Versus Chemotherapy Alone for Stage III Endometrial Cancer: A Multicenter Retrospective Study.

ABSTRACT:

Introduction

We aimed to evaluate the efficacy and toxicity of the combination of 6 cycles of chemotherapy and radiation therapy compared with chemotherapy alone as postoperative adjuvant therapy for patients with stage III endometrial cancer.

Methods

This retrospective cohort study included patients with stage III endometrial cancer who received postoperative chemoradiotherapy or chemotherapy alone at 6 hospitals between January 2009 and December 2019. The progression-free survival (PFS) and overall survival (OS) for each treatment group were analyzed using the Kaplan-Meier method. We also assessed differences in toxicity profiles between the treatment groups.

Results

A total of 133 patients met the inclusion criteria. Of these, 80 patients (60.2%) received adjuvant

SUBMITTER: Yoo JG 

PROVIDER: S-EPMC9297464 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature