Detection of canine distemper virus in cerebrospinal fluid, whole blood and mucosal specimens of dogs with distemper using RT-PCR and immunochromatographic assays.

ABSTRACT:

Background

Accurate diagnosis of canine distemper (CD), a highly contagious and acute viral disease, cannot be made solely based on clinical signs and haematological findings, but serological and molecular methods compatible with clinical signs are also required. The type of sample and method of tissue sampling are also very important. Sometimes in chronic cases, the canine distemper virus (CDV) may not be detected in blood and conjunctival specimens but can be detected in cerebrospinal fluid (CSF).

Objectives

The aim of this study was to evaluate and compare the suitability of CSF samples with whole blood and conjunctival samples in the detection of CDV.

Methods

The CDV was detected in CSF, whole blood and mucosal specimens in 20 dogs with obvious neurological with o

SUBMITTER: Sarchahi AA 

PROVIDER: S-EPMC9297742 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature