Thermoresistant Newcastle disease vaccine effectively protects SPF, native, and commercial chickens in challenge with virulent virus.

ABSTRACT:

Background

Due to the more stability and a better homogenecity in immune response, the use of thermoresistant vaccines in different chicken types has been increased.

Objective

This study aimed to evaluate the efficacy of a newly developed Newcastle disease vaccine (ND.TR.IR) originating from I-2 strain in specific pathogen-free (SPF) and native and broiler chickens.

Methods

Following determination of pathogenicity indices on the candidate seed, three efficacy examinations were conducted. In the first experiment, 120 1-day-old SPF chickens were randomly allocated to six groups and either vaccinated with ND.TR.IR via eye drop at 1, 7, and 21 days of age (V₁ , V₇ , and V₂₁ ), or considered as non-vaccinated control groups (C₁ ,

SUBMITTER: Abdoshah M 

PROVIDER: S-EPMC9297754 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature