Residual quadrupolar couplings observed in 7 Tesla deuterium MR spectra of skeletal muscle.

ABSTRACT:

Purpose

Deuterium metabolic imaging could potentially be used to investigate metabolism in skeletal muscle noninvasively. However, skeletal muscle is a tissue with a high degree of spatial organization. In this study, we investigated the effect of incomplete motional averaging on the naturally abundant deuterated water signal in 7 Tesla deuterium spectra of the lower leg muscles and the dependence on the angle between the muscle fibers and the main magnetic field B₀ , as determined by DTI.

Methods

Natural abundance deuterium MRSI measurements of the right lower leg muscles were performed at 7 Tesla. Three subjects were scanned in a supine position, with the right leg parallel with the B₀ field. One subject was scanned twice; during the second scan, the

SUBMITTER: Gursan A 

PROVIDER: S-EPMC9297863 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature