Characterization and risk factors of hyperglycaemia during treatment of childhood hematologic malignancies.

ABSTRACT:

Background

Secondary forms of diabetes are often understudied and underdiagnosed in children and adolescents with cancer. The objectives of our cohort study were to study the incidence and risk factors for hyperglycaemia in leukaemia and lymphoma patients.

Methods

We retrospectively collected 15 years of data from paediatric patients treated for acute lymphoblastic leukaemia (ALL), Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL) immediately at cancer diagnosis. We studied risk factors for hyperglycaemia in univariate and multivariate analyses.

Results

Our study cohort included 267 patients corresponding to 179 patients with ALL, 48 with NHL and 40 with HL. Eighteen per cent of ALL patients (32/179) and 17% of NHL patients (8/48) developed hyperglycaemia, wit

SUBMITTER: Welsch S 

PROVIDER: S-EPMC9297930 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature