Pessary or surgery for a symptomatic pelvic organ prolapse: the PEOPLE study, a multicentre prospective cohort study.

ABSTRACT:

Objective

To compare the 24-month efficacy of pessary or surgery as the primary treatment for symptomatic pelvic organ prolapse (POP).

Design

Multicentre prospective comparative cohort study.

Setting

Twenty-two Dutch hospitals.

Population

Women referred with symptomatic POP of stage ≥2 and moderate-to-severe POP symptoms.

Methods

The primary outcome was subjective improvement at the 24-month follow-up according to the Patient Global Impression of Improvement (PGI-I) scale. Secondary outcomes included improvement in prolapse-related symptoms measured with the Pelvic Floor Distress Inventory (PFDI-20), improvement in subjective severeness of symptoms according to the Patient Global Impression of Severity (PGI-S) scale and crossover between therapies. The p

SUBMITTER: van der Vaart LR 

PROVIDER: S-EPMC9298049 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature